| Bioactivity | PARP-2-IN-2 (compound 27) is a PARP‑2 inhibitor with an IC50 value of 0.057 µM. PARP-2-IN-2 induces cell cycle arrest and apoptosis of MCF-7 breast cancer cells. PARP-2-IN-2 can be used for the research of cancer[1]. |
| Invitro | PARP-2-IN-2 (0-1 μM; 1 h) inhibits PARP‑2 with an IC50 value of 0.057 µM[1].PARP-2-IN-2 (0-100 μM; 24 h) shows cytotoxicity to MDA-MB-231 and MCF-7 cancer cells[1].PARP-2-IN-2 (16.7 μM; 24 h) induces cell cycle arrest and apoptosis[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | PARP-2-IN-2 |
| Formula | C20H22ClN3O2 |
| Molar Mass | 371.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |