| Bioactivity | PAMP-12 is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM). PAMP-12 is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells[1]. | ||||||
| Name | PAMP-12 | ||||||
| CAS | 929905-12-4 | ||||||
| Sequence | Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg | ||||||
| Shortening | FRKKWNKWALSR | ||||||
| Formula | C77H118N24O15 | ||||||
| Molar Mass | 1619.91 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
PAMP-12
CAS: 929905-12-4 F: C77H118N24O15 W: 1619.91
PAMP-12 is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM).PAMP-12 is an endogenous peptide that elicit hypotension thr
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