| Bioactivity | PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist. |
| Invitro | PAF-AN-1 is extracted from patent EP0469477A1, page 2, line 47[1]. PAF-AN-1 is a 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline analog. PAF-AN-1 inhibits PAF-induced bronchoconstriction and hemoconcentration when administered po to the guinea pig[2]. |
| Name | PAF-AN-1 |
| CAS | 115621-84-6 |
| Formula | C28H28N2O3 |
| Molar Mass | 440.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. EP0469477A1 [2]. Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102. |