| Bioactivity | P4pal10 is a PAR4 antagonist. P4pal10 prevents the thrombin-mediated aggregation of mouse platelets in vivo. P4pal10 significantly reduced both the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474)[1]. |
| Target | PAR4 |
| Name | P4pal10 |
| CAS | 1021346-05-3 |
| Sequence | {Pal}-Ser-Gly-Arg-Arg-Tyr-Gly-His-Ala-Leu-Arg-NH2 |
| Shortening | {Pal}-SGRRYGHALR-NH2 |
| Formula | C65H112N22O13 |
| Molar Mass | 1409.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Houle S, et al. Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents. Br J Pharmacol. 2005 Nov;146(5):670-8. |
P4pal10
CAS: 1021346-05-3 F: C65H112N22O13 W: 1409.72
P4pal10 is a PAR4 antagonist. P4pal10 prevents the thrombin-mediated aggregation of mouse platelets in vivo. P4pal10 sig
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