| Bioactivity | P2Y6R antagonist 1 (compound 5ab) is a selective, orally active P2Y6R antagonist with a IC50 value of 19.6 nM. P2Y6R antagonist 1 has anti-inflammatory activity[1]. |
| Formula | C20H18N4O3 |
| Molar Mass | 362.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao Y, et al. Discovery of a potent, Highly selective, and In vivo anti-inflammatory Efficacious, P2Y6R antagonist with a novel quinoline-pyrazole scaffold. Eur J Med Chem. 2024 Sep 23;279:116890. |