| Bioactivity | P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease[1]. |
| Target | IC50: 0.01 nM (human whole blood IL-Iβ release) |
| Invitro | P2X7-IN-2 (0-1 μM;30 min) inhibits human whole blood IL-Iβ release with an IC50 value of 0.01 nM[1]. |
| Name | P2X7-IN-2 |
| CAS | 1058709-63-9 |
| Formula | C22H21F4N3O2 |
| Molar Mass | 435.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008. |
P2X7-IN-2
CAS: 1058709-63-9 F: C22H21F4N3O2 W: 435.41
P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.