PeptideDB

P110

CAS: 1411976-18-5 F: C32H56N10O11 W: 756.85

P110, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia,
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Bioactivity P110, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1[1].
In Vivo P110在多种人类疾病的动物模型中表现出巨大益处,但由于P110对血清和细胞蛋白酶敏感,且不能通过口服方式吸收,因此将其转化为临床干预受到限制。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 1411976-18-5
Sequence Asp-Leu-Leu-Pro-Arg-Gly-Ser
Shortening DLLPRGS
Formula C32H56N10O11
Molar Mass 756.85
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Luis Rios, et al. Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun. 2023 Jul 19;14(1):4356.