Bioactivity | P-gp inhibitor 17 (compound 2g) is a P-gp inhibitor directly interacted with the transmembrane domain of P-gp. P-gp inhibitor 17 can be used for P-gp-mediated multidrug-resistant in tumor cells study[1]. |
Name | P-gp inhibitor 17 |
CAS | 2556388-58-8 |
Formula | C36H49N3O3 |
Molar Mass | 571.79 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ziqian Wang, et al. Exploiting the “Hot-Spots” of Hsp70–Bim Protein–Protein Interaction to Optimize the 1-Oxo-1H-phenalene-2,3-dicarbonitrile Analogues as Specific Hsp70–Bim Inhibitors. .Med. Chem. 2023, 66, 23, 16377–16387Publication Date:November 27, 2023 |