PeptideDB

Oxythiamine diphosphate

CAS: 10497-04-8 F: C12H17N3O8P2S W: 425.29

Oxythiamin diphosphate is a potent transketolase (TK) inhibitor.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Oxythiamin diphosphate is a potent transketolase (TK) inhibitor[1].
Target Ki: 30 nM (thiamine pyrophosphate).
Invitro Rat liver TK is inhibited at 50% by oxythiamine diphosphate in concentrations of 0.02–0.2 μM. I50 value of Oxythiamine diphosphate for yeast transketolase is approximately 0.03 μM[1].
Name Oxythiamine diphosphate
CAS 10497-04-8
Formula C12H17N3O8P2S
Molar Mass 425.29
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Tylicki A, et al. Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis. Biosci Rep. 2018;38(1):BSR20171148. Published 2018 Jan 10.