Bioactivity | Oxythiamin diphosphate is a potent transketolase (TK) inhibitor[1]. |
Target | Ki: 30 nM (thiamine pyrophosphate). |
Invitro | Rat liver TK is inhibited at 50% by oxythiamine diphosphate in concentrations of 0.02–0.2 μM. I50 value of Oxythiamine diphosphate for yeast transketolase is approximately 0.03 μM[1]. |
Name | Oxythiamine diphosphate |
CAS | 10497-04-8 |
Formula | C12H17N3O8P2S |
Molar Mass | 425.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tylicki A, et al. Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis. Biosci Rep. 2018;38(1):BSR20171148. Published 2018 Jan 10. |