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Oxythiamine diphosphate ammonium

CAS: F: W:

Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor.
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Bioactivity Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor[1].
Invitro Rat liver TK was inhibited at 50% by oxythiamine diphosphate ammonium in concentrations of 0.02-0.2 μM. I50 value of Oxythiamine diphosphate ammonium for yeast transketolase is approximately 0.03 μM[1].
Name Oxythiamine diphosphate ammonium
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Reference [1]. Tylicki A, et al. Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis. Biosci Rep. 2018;38(1):BSR20171148. Published 2018 Jan 10.