Oxyfluorfen-d5_product_DataBase

Bioactivity	Oxyfluorfen-d5 is deuterated labeled Oxyfluorfen (HY-119176) Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis.
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Oxyfluorfen-d5 相关抗体:
CAS	2140327-69-9
Formula	C15H6D5ClF3NO4
Molar Mass	366.73
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Chi Wu, et al. Sorption, Degradation and Bioavailability of Oxyfluorfen in Biochar-Amended Soils. Sci Total Environ. 2019 Mar 25;658:87-94. [3]. E Warabi, et al. Resistance of a Soybean Cell Line to Oxyfluorfen by Overproduction of Mitochondrial Protoporphyrinogen Oxidase. Pest Manag Sci. 2001 Aug;57(8):743-8.

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