| Bioactivity | Oxybutynin-d11 (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | Oxybutynin-d11 (chloride) |
| CAS | 1185151-95-4 |
| Formula | C22H21D11ClNO3 |
| Molar Mass | 405.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Li H, The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036. |
Oxybutynin-d11 (chloride)
CAS: 1185151-95-4 F: C22H21D11ClNO3 W: 405.02
Oxybutynin-d11 (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent,
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