| Bioactivity | Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest[1][2][3]. |
| Invitro | Oxiconazole (24 h; 0-40 μM) inhibits CRC cell growth[3].Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton[1].Antifungal Activities of Oxiconazole[1]. |
| Name | Oxiconazole nitrate |
| CAS | 64211-46-7 |
| Formula | C18H14Cl4N4O4 |
| Molar Mass | 492.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Oxiconazole nitrate
CAS: 64211-46-7 F: C18H14Cl4N4O4 W: 492.14
Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergil
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