| Bioactivity | Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibits the oxidation of fatty acid in heart. Oxfenicine protects heart from necrotic tissue damage during ischaemia[1][2]. | ||||||||||||
| Target | carnitine palmitoyltransferase-1 | ||||||||||||
| Name | Oxfenicine | ||||||||||||
| CAS | 32462-30-9 | ||||||||||||
| Formula | C8H9NO3 | ||||||||||||
| Molar Mass | 167.16 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Stephens TW, et, al. Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine. Biochem J. 1985 Apr 15;227(2):651-60. [2]. Greaves P, et, al. Cardiac hypertrophy in the dog and rat induced by oxfenicine, an agent which modifies muscle metabolism. Arch Toxicol Suppl. 1984;7:488-93. |
Oxfenicine
CAS: 32462-30-9 F: C8H9NO3 W: 167.16
Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibit
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