| Bioactivity | Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma[1]. |
| Invitro | Oxelumab (10 μg/mL；3 天) 抑制 NK 细胞的增殖[2]. Cell Proliferation Assay[2] Cell Line: |
| In Vivo | Oxelumab (5 和 30 mg/kg；腹腔注射，每天一次，共两次) 影响 IL-6 的浓度和脾人效应记忆 T 细胞和开关 B 细胞的频率[1]。 Animal Model: |
| Name | Oxelumab |
| CAS | 1186098-83-8 |
| Appearance | Liquid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180(2):91-102. [2]. Kweon S, et al. Expansion of Human NK Cells Using K562 Cells Expressing OX40 Ligand and Short Exposure to IL-21. Front Immunol. 2019 Apr 24;10:879. |