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Oxalomalic acid trisodium

CAS: 89304-26-7 F: C6H3Na3O8 W: 272.05

Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic
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Bioactivity Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages[1].
Invitro Oxalomalic acid trisodium (2.2, 5 mM; 2+24 h) 可减少 J774 细胞中 LPS 诱导的亚硝酸盐产生和 iNOS 蛋白表达[1]。Oxalomalic acid trisodium (5 mM; 6, 12 h) 对 LPS 刺激的 J774 巨噬细胞中 iNOS mRNA 的表达没有影响[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Oxalomalic acid trisodium 相关抗体: Western Blot Analysis[1] Cell Line:
CAS 89304-26-7
Formula C6H3Na3O8
Molar Mass 272.05
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Irace C, et al. Oxalomalate affects the inducible nitric oxide synthase expression and activity. Life Sci. 2007 Mar 13;80(14):1282-91.