Bioactivity | Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages[1]. |
Invitro | Oxalomalic acid trisodium (2.2, 5 mM; 2+24 h) 可减少 J774 细胞中 LPS 诱导的亚硝酸盐产生和 iNOS 蛋白表达[1]。Oxalomalic acid trisodium (5 mM; 6, 12 h) 对 LPS 刺激的 J774 巨噬细胞中 iNOS mRNA 的表达没有影响[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Oxalomalic acid trisodium 相关抗体: Western Blot Analysis[1] Cell Line: |
CAS | 89304-26-7 |
Formula | C6H3Na3O8 |
Molar Mass | 272.05 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Irace C, et al. Oxalomalate affects the inducible nitric oxide synthase expression and activity. Life Sci. 2007 Mar 13;80(14):1282-91. |