| Bioactivity | Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. Osteogenic Growth Peptide (10-14) is responsible for the binding to the OGP receptor and activates an intracellular Gi-protein-MAP kinase signaling pathway. Osteogenic Growth Peptide (10-14) is a potent mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acts as a Src inhibitor[1][2][3][4]. | ||||||
| Invitro | Osteogenic Growth Peptide (10-14) (OGP(10-14)) induces proliferation and differentiation in fibroblast and osteoblast cell lines[3].Osteogenic Growth Peptide (10-14) induces TPO-primed M07-e cells differentiation through RhoA/TGFβ1/SFKs signalling pathway. In particular Historphin acts as a Src inhibitor, showing the same effects of PP2[4]. | ||||||
| Name | Osteogenic Growth Peptide (10-14) | ||||||
| CAS | 105250-85-9 | ||||||
| Shortening | YGFGG | ||||||
| Formula | C24H29N5O7 | ||||||
| Molar Mass | 499.52 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Osteogenic Growth Peptide (10-14)
CAS: 105250-85-9 F: C24H29N5O7 W: 499.52
Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP)
Data collection：peptidedb@qq.com
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