Orotirelin_product_DataBase

Bioactivity	Orotirelin (CG 3509) is a thyrotrophin-releasing hormone (TRH) analogue. Orotirelin can be used in the study of neurological diseases[1].
In Vivo	在戊巴比妥麻醉大鼠中，向伏隔核双侧注射 Orotirelin（0.1-1.0 μg）可减少戊巴比妥诱导的睡眠时间[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	62305-86-6
Formula	C16H19N7O5
Molar Mass	389.37
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. K C Fone, et al. Involvement of 5-HT2 receptors in the behaviours produced by intrathecal administration of selected 5-HT agonists and the TRH analogue (CG 3509) to rats. Br J Pharmacol. 1989 Mar;96(3):599-608. [2]. T Sharp, et al. Analeptic effects of centrally injected TRH and analogues of TRH in the pentobarbitone-anaesthetized rat. Neuropharmacology. 1984 Mar;23(3):339-48.

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