Bioactivity | Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1]. | ||||||||||||
Name | Orexin receptor antagonist 2 | ||||||||||||
CAS | 1457940-75-8 | ||||||||||||
Formula | C25H31N5O2 | ||||||||||||
Molar Mass | 433.55 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607. |