| Bioactivity | Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC)[1][2]. |
| Name | Orellanine |
| CAS | 37338-80-0 |
| Formula | C10H8N2O6 |
| Molar Mass | 252.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lyons MJ, et al. Orellanine: From Fungal Origin to a Potential Future Cancer Treatment. J Nat Prod. 2023 Jun 23;86(6):1620-1631. [2]. Buvall L, et al. Orellanine specifically targets renal clear cell carcinoma. Oncotarget. 2017 Jul 25;8(53):91085-91098. |