Bioactivity | Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2]. |
In Vivo | Oosponol (6.25 mg/kg, 3.1 mg/kg, 腹腔注射, 使用1次) 在自发性高血压大鼠模型中降低了大鼠的血压[1] Animal Model: |
Name | Oosponol |
CAS | 146-04-3 |
Formula | C11H8O5 |
Molar Mass | 220.18 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9. |