| Bioactivity | Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease[1]. |
| Target | mucosal addressin cell adhesion molecule-1 (MAdCAM-1) |
| Invitro | Ontamalimab 以高亲和力选择性结合 MAdCAM-1，诱导特定白细胞亚群的运输[1]。 |
| Name | Ontamalimab |
| CAS | 2098790-40-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. D'Haens GR, et, al. Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study. Inflamm Bowel Dis. 2022 Jul 1;28(7):1034-1044. |