| Bioactivity | Ono 3307 Free base is a novel synthetic protease inhibitor that exhibits protective effects against acute pancreatitis by preventing hyperamylasemia and pancreatic edema. Ono 3307 Free base also inhibits the redistribution of lysosomal enzymes in acinar cells and mitigates lactic dehydrogenase discharge. Ono 3307 Free base effectively reduces cathepsin B leakage from lysosomes in a dose-dependent manner. |
| CAS | 76472-28-1 |
| Formula | C14H14N4O4S |
| Molar Mass | 334.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Protection by a new synthetic protease inhibitor, ONO3307, of the rat exocrine pancreas during acute edematous pancreatitis induced by a supramaximal dose of caerulein in comparison with FOY007 |
Ono 3307 free base
CAS: 76472-28-1 F: C14H14N4O4S W: 334.35
Ono 3307 Free base is a novel synthetic protease inhibitor that exhibits protective effects against acute pancreatitis b
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