Omzotirome_product_DataBase

Bioactivity	Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379)[1][2].
In Vivo	Omzotirome (0.750 mg/ 100 g; i.p.) with high-fat diet rats have significantly less visceral adipose tissue (vs. HFD rats) and exhibit altered metabolism in two major tissues that are very active metabolically and exhibit increased energy expenditure and body weight (BW) gain comparable to that of standard chow-fed rats[1].Omzotirome, a functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet (HFD)[1]. Animal Model:
Name	Omzotirome
CAS	1092551-88-6
Formula	C19H24N2O3
Molar Mass	328.41
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Reference	[1]. WO2008149379 [2]. Cioffi F, et al. TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet. FASEB J. 2010;24(9):3451-3461.

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