Olomoucine II_product_DataBase

Bioactivity	Olomoucine II is a potent CDK inhibitor with IC50 values of 0.06, 0.1, 0.45, 7.6, 19.8 µM for CDK9/cyclin T, CDK2/cyclin E, CDK7/cyclin H, CDK1/cyclin B, CDK4/cyclin D1, respectively. Olomoucine II shows antiproliferative activity[1].
Invitro	Olomoucine II (72 h) 显示出抗增殖活性，对 HOS、T98G、HBL100、BT474、MCF-7、HT-29、CCRF-CEM、BV173 和 HL60 细胞的 IC50 值分别为 9.3、9.2、10.5、13.6、5.0、10.8、5.3、2.7、16.3 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Olomoucine II 相关抗体: Cell Proliferation Assay[1] Cell Line:
CAS	500735-47-7
Formula	C19H26N6O2
Molar Mass	370.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Krystof V, et al. Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor. Cell Mol Life Sci. 2005 Aug;62(15):1763-71.

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