| Bioactivity | Olinone is a selective BRD4 BrD1 inhibitor[1]. Olinone accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation[2]. |
| Name | Olinone |
| CAS | 1770789-37-1 |
| Formula | C17H21N3O2 |
| Molar Mass | 299.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rodríguez Y, et al. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4. Proteins. 2020 Mar;88(3):414-430. [2]. Gacias M, et al. Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. Chem Biol. 2014 Jul 17;21(7):841-854. |