Oleyl anilide_product_DataBase

Bioactivity	Oleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS). Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM)[1][2].
In Vivo	Oleyl anilide (0.8 mmol/kg，腹腔注射，每周两次，持续 6 周) 会引起雌性 MRL+/+ 小鼠免疫反应扰动，并出现 TOS 相关的免疫紊乱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	5429-85-6
Formula	C24H39NO
Molar Mass	357.57
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Roth BD, et al. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. J Med Chem. 1992 May 1;35(9):1609-17. [2]. Cai P, et al. Immunotoxic response of oleic acid anilide and its hydrolysis products in female MRL (+/+) mice. J Immunotoxicol. 2005 Oct 1;2(4):231-6.

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