| Bioactivity | Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule. | ||||||||||||
| Invitro | Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. HY-18003 is extracted from the reference, compound 12a. For the transformation of olefin 9a (HY-18002) into ketone 12a (HY-18003), the obvious ozonolysis cannot be used because ozone also reacts with the C-12 olefin of oleanane triterpenoids to give the 12R,13R-epoxide, 12-ketone,9 and 12R-hydroxy lactone.[1]. | ||||||||||||
| Name | Oleanolic acid derivative 2 | ||||||||||||
| CAS | 211516-63-1 | ||||||||||||
| Formula | C28H42O3 | ||||||||||||
| Molar Mass | 426.63 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849. |
Oleanolic acid derivative 2
CAS: 211516-63-1 F: C28H42O3 W: 426.63
Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
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