| Bioactivity | Oleanolic acid derivative 1 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule. | ||||||||||||
| Invitro | Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. HY-18002 is extracted from the reference, compound 9a. In the strategy, it was ambiguous whether phosphorus pentachloride (PCl5) would give the desired ring contraction product 9a (HY-18002) in the first step according to classical procedures[1]. | ||||||||||||
| Name | Oleanolic acid derivative 1 | ||||||||||||
| CAS | 1724-18-1 | ||||||||||||
| Formula | C31H48O2 | ||||||||||||
| Molar Mass | 452.71 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849. |