| Bioactivity | OfHex1-IN-1 (compound 11c) is a potent and selective OfHex1 (β-N-acetylhexosaminidase from Ostrinia furnacalis) inhibitor, with an IC50 of 28.1 μM and a Ki of 25.6 μM. OfHex1-IN-1 can be used for OfHex1-related green pesticides research[1]. |
| Target | IC50: 28.1 ± 1.6 μM (OfHex1), > 100 μM (hOGA), > 100 μM (HsHexB) |
| Name | OfHex1-IN-1 |
| Formula | C31H42N4O7S |
| Molar Mass | 614.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shen S, Dong L, Lu H, Dong Y, Yang Q, Zhang J. Synthesis of ureido thioglycosides as novel insect β‑N‑acetylhexosaminidase OfHex1 inhibitors. Bioorg Med Chem. 2020 Aug 1;28(15):115602. |