Bioactivity | Odesivimab is a humanized monoclonal antibody, targeting Ebola virus glycoprotein with a KD value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection[1]. |
Invitro | Odesivimab (REGN-3471) 在体外中和假病毒颗粒。Odesivimab 与 Atoltivimab 和 Maftivimab 的 IC50 值为 0.39 nM[1]。 |
In Vivo | Odesivimab 与 Atoltivimab 和Maftivimab (REGN-3471; 50 mg/kg) 对埃博拉病毒感染的恒河猴模型具有保护作用[1]。 |
Name | Odesivimab |
CAS | 2135632-30-1 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Markham A. REGN-EB3: First Approval. Drugs. 2021 Jan;81(1):175-178. |