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Obidoxime dichloride

CAS: 114-90-9 F: C14H16Cl2N4O3 W: 359.21

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent p
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Bioactivity Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].
In Vivo Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1]. Animal Model:
Name Obidoxime dichloride
CAS 114-90-9
Formula C14H16Cl2N4O3
Molar Mass 359.21
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kassa J,et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25(3):229-33.