| Bioactivity | OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1]. |
| Target | Ki: 17.6 µM (GGT) |
| Invitro | OU749 (compound 3) (3 days) 对 786-O 细胞具有细胞毒性，LD50 值为 128 µM[1]。OU749 (0-1000 µM) 在 786-O 和 HK-2 细胞中以剂量依赖性方式抑制 GGT (γ-谷氨酰转肽酶) 活性[1]。 |
| Name | OU749 |
| CAS | 519170-13-9 |
| Formula | C16H15N3O3S2 |
| Molar Mass | 361.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. King JB, et al. A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 3;284(14):9059-65. |