Bioactivity | OSU-ERb-12 is a ERβ agonist, and suppress ovarian cancer cell proliferation in vitro and in vivo. OSU-ERb-12 decreases the expression of Snail[1][2]. |
CAS | 2088837-20-9 |
Formula | C15H30B10O2 |
Molar Mass | 350.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sedlák D, et al. Structure-Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists. J Med Chem. 2021;64(13):9330-9353. [2]. Banerjee A, et al. A Novel Estrogen Receptor β Agonist Diminishes Ovarian Cancer Stem Cells via Suppressing the Epithelial-to-Mesenchymal Transition. Cancers (Basel). 2022;14(9):2311. Published 2022 May 6. |