| Bioactivity | ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in prostate cancer cells. ONC1-13B can effectively inhibit PSA expression and prostate cancer cell proliferation under DHT stimulation. ONC1-13B exerts its anti-tumor effect by preventing androgen from binding to AR and its nuclear translocation[1]. |
| CAS | 1351185-54-0 |
| Formula | C22H16F4N4O3S |
| Molar Mass | 492.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Preclinical Development of ONC1-13B, Novel Antiandrogen for Prostate Cancer Treatment |
ONC1-13B
CAS: 1351185-54-0 F: C22H16F4N4O3S W: 492.45
ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in pro
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