| Bioactivity | O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM[1][2]. |
| Target | Ki: 58 μM (Factor Xa) |
| Name | O-Desmethyl apixaban sulfate sodium |
| Formula | C24H22N5NaO7S |
| Molar Mass | 547.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wong PC, et al. Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor. J Thromb Thrombolysis. 2011 May;31(4):478-92. [2]. Wang L, et al. Sulfation of o-demethyl apixaban: enzyme identification and species comparison. Drug Metab Dispos. 2009 Apr;37(4):802-8. |
O-Desmethyl apixaban sulfate sodium
CAS: F: C24H22N5NaO7S W: 547.52
O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfat
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