| Bioactivity | O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin (HY-14397). It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase. It has also been used in the synthesis of prostaglandin D2 (HY-101988) receptor antagonists. |
| CAS | 50995-53-4 |
| Formula | C₁₁H₁₁NO₃ |
| Molar Mass | 205.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Torisu, et al. Discovery of new chemical leads for prostaglandin D2 receptor antagonists. Bioorg. Med. Chem. Lett. 14(17), 4557-4562 (2004). |
O-Desmethyl-N-deschlorobenzoyl Indomethacin
CAS: 50995-53-4 F: C₁₁H₁₁NO₃ W: 205.21
O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX
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