| Bioactivity | O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV[1]. |
| Name | O-Desmethyl Brinzolamide hydrochloride |
| CAS | 2967475-56-3 |
| Formula | C11H20ClN3O5S3 |
| Molar Mass | 405.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qinhua Huang, et al. Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure. J Med Chem. 2015 Mar 26;58(6):2821-33. |
O-Desmethyl Brinzolamide hydrochloride
CAS: 2967475-56-3 F: C11H20ClN3O5S3 W: 405.94
O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA)
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