| Bioactivity | O,O-Dimethyl-cannabigerol is a natural product from Cannabis sativa. O,O-Dimethyl-cannabigerol has an antibacterial effect on drug-resistant strains of Staphylococcus aureus (MIC ranging from 1 to 2 µg/mL)[1]. O,O-Dimethyl-cannabigerol is a nonpsychoactive constituent[2][3]. | ||||||||||||
| Invitro | O,O-Dimethyl-cannabigerol (compound 1) inhibits KB cells growth with IC50s of 44.55 μM (MTT assay) and 69.4 μM (SRB assay)[2].O,O-Dimethyl-cannabigerol (0-100 μM; 48 hours) induces cell cytotoxic in NIH 3T3 fibroblasts, with CD50s of 60.46 μM (MTT assay) and 82.98 μM (SRB assay)[2].O,O-Dimethyl-cannabigerol shows antitumor efficacy against melanoma cells of a mouse's skin with an IC50 of 31.3 μM[2]. Cell Cytotoxicity Assay[2] Cell Line: | ||||||||||||
| Name | O,O-Dimethyl-cannabigerol | ||||||||||||
| CAS | 29106-16-9 | ||||||||||||
| Formula | C23H36O2 | ||||||||||||
| Molar Mass | 344.53 | ||||||||||||
| Appearance | Liquid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Appendino G, et al. Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. J Nat Prod. 2008;71(8):1427-1430. [2]. Han DS, et al. Synthesis and cytotoxic effects of deoxy-tomentellin. Arch Pharm Res. 2000;23(2):121-127. [3]. Caprioglio D, et al. O-Methyl Phytocannabinoids: Semi-synthesis, Analysis in Cannabis Flowerheads, and Biological Activity. Planta Med. 2019;85(11-12):981-986. |
O,O-Dimethyl-cannabigerol
CAS: 29106-16-9 F: C23H36O2 W: 344.53
O,O-Dimethyl-cannabigerol is a natural product from Cannabis sativa. O,O-Dimethyl-cannabigerol has an antibacterial effe
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