| Bioactivity | Nutlin 1, an antagonist of MDM2, activates a major cellular function of the p53 pathway, with an IC50 value of 0.26 μM[1]. |
| CAS | 548472-58-8 |
| Formula | C32H34Cl2N4O4 |
| Molar Mass | 609.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lyubomir T Vassilev, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science. 2004 Feb 6;303(5659):844-8. |
Nutlin 1
CAS: 548472-58-8 F: C32H34Cl2N4O4 W: 609.54
Nutlin 1, an antagonist of MDM2, activates a major cellular function of the p53 pathway, with an IC50 value of 0.26 μM.
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