Nurr1 agonist 2_product_DataBase

CAS: 742058-34-0 F: C18H14O3S W: 310.37

Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 3 binds to the recombinant Nurr1 ligand

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 3 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 3 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].
Name	Nurr1 agonist 2
CAS	742058-34-0
Formula	C18H14O3S
Molar Mass	310.37
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ballarotto M, et al.De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66(12):8170-8177.

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