Bioactivity | Nrf2 (69-84) is a peptide fragment of Nrf2 protein that contains the key ETGE motif, which is an important region for binding to the Kelch domain of Keap1 protein. Nrf2 (69-84) can be used to study the role of Nrf2 in the development and progression of diseases, especially in cancer, neurodegenerative diseases and inflammatory diseases[1]. |
CAS | 1364173-77-2 |
Sequence | Ala-Phe-Phe-Ala-Gln-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu |
Shortening | AFFAQLQLDEETGEFL |
Formula | C86H124N18O28 |
Molar Mass | 1858.01 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen Y, et al. Kinetic analyses of Keap1–Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance[J]. Chemical biology & drug design, 2011, 78(6): 1014-1021. |