Bioactivity | NoxaBH3 is a cysteine-based cross-linked peptide with increased cell permeability and higher inhibitory activity against Mcl-1. NoxaBH3 binds to the endogenous CXCR4 ligand to produce ubiquitin-Noxabh3 conjugate. NoxaBH3 is then delivered to cancer cells[1]. |
Name | NoxaBH3 |
Sequence | Ala-Ala-Cys-Leu-Arg-Arg-Ile-Gly-Asp-Cys-Val-Asn-Leu-Arg-Gln-Lys-Leu-Leu-Asn |
Shortening | AACLRRIGDCVNLRQKLLN |
Formula | C90H162N32O25S2 |
Molar Mass | 2156.68 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |