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Norsufentanil

CAS: 61086-18-8 F: C16H24N2O2 W: 276.37

Sufentanil is a potent synthetic opioid analgesic. Norsufentanil, a metabolite of sufentanil, is produced by the oxidati
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Bioactivity Sufentanil is a potent synthetic opioid analgesic. Norsufentanil, a metabolite of sufentanil, is produced by the oxidative N-dealkylation of the liver cytochrome P450 isomer. Norsufentanil has analgesic activity[1][2].
CAS 61086-18-8
Formula C16H24N2O2
Molar Mass 276.37
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Nami M, et al. Synthesis of novel norsufentanil analogs via a four-component Ugi reaction and in vivo, docking, and QSAR studies of their analgesic activity. Chem Biol Drug Des. 2018 Apr;91(4):902-914. [2]. Tateishi T, et al. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. Anesth Analg. 1996 Jan;82(1):167-72.