| Bioactivity | NorA-IN-2 (compound DZ-3) is a potent NorA inhibitor. NorA-IN-2 shows NorA efflux pump inhibitors (EPI) activity[1]. |
| Invitro | NorA-IN-2 (compound DZ-3) 显示出抗菌活性，对 Staphylococcus aureus (S. aureus) 1199B, S. aureus RN4220,S. aureus XU212, E. coli AG100 的 MIC 值分别为 8、256、128、128 µg/mL[1]。NorA-IN-2 (300, 400, 500 µg/mL; 24 h) 显示对 RAW 264.7、HaCaT 细胞的细胞毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> NorA-IN-2 相关抗体: Cell Cytotoxicity Assay[1] Cell Line: |
| Formula | C22H24ClN3 |
| Molar Mass | 365.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. A Malik A, et al. Discovery of novel dihydronaphthalene-imidazole ligands as potential inhibitors of Staphylococcus aureus multidrug resistant NorA efflux pump: A combination of experimental and in silico molecular docking studies. Microb Pathog. 2024 Mar 21;190:106627. |