| Bioactivity | Nonactin is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+[1]. Nonactin is able to uncouple the oxidative phosphorylation (OXPHOS) of mitochondria. Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin[2]. Nonactin inhibits the surface expression of endogenous HSP60[3]. | |||||||||
| Name | Nonactin | |||||||||
| CAS | 6833-84-7 | |||||||||
| Formula | C40H64O12 | |||||||||
| Molar Mass | 736.93 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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Nonactin
CAS: 6833-84-7 F: C40H64O12 W: 736.93
Nonactin is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for
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