Bioactivity | Nitisinone (Standard) is the analytical standard of Nitisinone. This product is intended for research and analytical applications. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism. |
CAS | 104206-65-7 |
Formula | C14H10F3NO5 |
Molar Mass | 329.23 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |