| Bioactivity | Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research[1]. Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[4]. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells[2][3][5]. | ||||||||||||
| Invitro | Niclosamide (0.6 nM-46 µM) treatment inhibits adrenocortical carcinoma cellular proliferation in BD140A, SW-13, and NCI-H295R cells[3].Niclosamide (0.05-5 μM, 24 h) treatment inhibits STAT3-mediated luciferase reporter activity in HeLa cells [4].Niclosamide (10 μM) treatment inhibits virus replication in Vero E6 cells[5]. Cell Viability Assay[3] Cell Line: | ||||||||||||
| Name | Niclosamide | ||||||||||||
| CAS | 50-65-7 | ||||||||||||
| Formula | C13H8Cl2N2O4 | ||||||||||||
| Molar Mass | 327.12 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Niclosamide
CAS: 50-65-7 F: C13H8Cl2N2O4 W: 327.12
Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research. Niclosamide is a ST
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