Bioactivity | Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research[1]. Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[4]. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells[2][3][5]. |
Invitro | 氯硝柳胺 (0.6 nM-46 μ M) 处理可抑制 BD140A、SW-13 和 NCI-H295R 细胞的肾上腺皮质癌细胞增殖[3]。氯硝柳胺 (0.05-5 μM, 24 h) 处理抑制 STAT3 介导的 HeLa 细胞荧光素酶报告活性[4]。氯硝柳胺 (10 μM) 处理抑制病毒在 Vero E6 细胞中的复制[5]。 Cell Viability Assay[3] Cell Line: |
Name | Niclosamide olamine |
CAS | 1420-04-8 |
Formula | C15H15Cl2N3O5 |
Molar Mass | 388.20 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |