| Bioactivity | Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research[1]. Niclosamide monohydrate is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[4]. Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells[2][3][5]. |
| Invitro | Niclosamide monohydrate (0.6 nM-46 µM) treatment inhibits adrenocortical carcinoma cellular proliferation in BD140A, SW-13, and NCI-H295R cells[3].Niclosamide monohydrate (0.05-5 μM, 24 h) treatment inhibits STAT3-mediated luciferase reporter activity in HeLa cells [4].Niclosamide monohydrate (10 μM) treatment inhibits virus replication in Vero E6 cells[5]. Cell Viability Assay[3] Cell Line: |
| Name | Niclosamide monohydrate |
| CAS | 73360-56-2 |
| Formula | C13H10Cl2N2O5 |
| Molar Mass | 345.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Niclosamide monohydrate
CAS: 73360-56-2 F: C13H10Cl2N2O5 W: 345.13
Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research. Niclosa
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